Grapefruit

For many children of the 70s and 80s, the grapefruit is remembered as an icon, a symbol of thinning up and the "grapefruit diet," which posited that the fruit had fat-burning enzymes. Though the premise has since been debunked, grapefruit remains a popular choice for its health benefits and refreshing taste.

Grapefruit and its juice can interact with certain medications, increasing their absorption into the bloodstream, which can lead to potentially serious side effects. This includes some statins (cholesterol-lowering drugs), and medications for conditions like hypertension and arrhythmia. Therefore, it's always recommended to consult with a healthcare provider when consuming grapefruit while on medication.

There is a potential issue that’s unique to many citrus: How they’re consumed, at least in the United States and Western Europe. Lemons are often either squeezed for their juice or zested for their peel. The pith and sometimes even the flesh are discarded. So it’s difficult to take a measure of lemon and say for sure what benefit you’re getting if you’re discarding one of the parts. The same goes for limes. Grapefruit and orange flesh is often consumed, along with some of the pith, however the peel is often discarded. Only kumquats amongst the citrus are commonly consumed whole: peel, pith, flesh, juice and all.